Zestoretic (lisinopril and hydrochlorothiazide) is a combination of an angiotension converting enzyme (ACE) inhibitor and a diuretic used to treat high blood pressure (hypertension).Zestoretic is available in generic form.. What Are Side Effects of Zestoretic? Gas 12. Brown CW, Deng JS "Thiazide diuretics induce cutaneous lupus-like adverse reaction." Less common side effects include nausea, vomiting, weakness, fast or uneven heartbeat, muscle pain or weakness, numbness, skin rash, impotence or low fever 1. lack or loss of strength. I have been reading about side effects of the Three medications I take, they all mention side effects of pain like the ones I have experienced. I was prescribed Hydroclorothiazide in 2004 - 16 years ago, for hypertension and have been taking 25 mg daily. N Engl J Med 321 (1989): 868-73, 15. Common side effects of Microzide include weakness, low blood pressure, light sensitivity, … If you are concerned about side effects, discuss the … [Ref], Frequency not reported: Anaphylactic reactions, necrotizing angiitis (vasculitis and cutaneous vasculitis), respiratory distress (including pneumonitis and pulmonary edema), photosensitivity, fever, urticaria, rash, purpura, toxic epidermal necrolysis[Ref], There have been approximately 34 known cases of thiazide-induced pulmonary edema, encompassing 52 episodes of pulmonary edema, as of 1991 (per a 1996 review). Hydrochlorothiazide is a diuretic (this means it increases urination) that works … Bain PG, Egner W, Walker PR "Thiazide-induced dilutional hyponatraemia masquerading as subarachnoid haemorrhage ." Common side effects include: 1. For the Consumer. Prupas HM, Brown D "Acute idiosyncratic reaction to hydrochlorothiazide ingestion." High Blood Sugar 2. Am J Health Syst Pharm 62 (2005): 2630-3, 68. There are rare case reports of hydrochlorothiazide-induced immune hemolytic anemia. Read reviews from GoodRx users who … Chittivelu S "Hydrochlorothiazide-induced pulmonary edema and associated immunologic changes." You may report side effects to the FDA at 1-800-FDA-1088. Fichman MP, Vorherr H, Kleeman CR, Telfer N "Diuretic-induced hyponatremia." The most common side effects of taking hydrochlorothiazide are diarrhea, constipation, stomach ache, dizziness, and/or blurred vision. Delevett AF, Recalde M "Diuretic-induced renal colic." Common hydrochlorothiazide side effects may include: nausea, vomiting, loss of appetite; diarrhea, constipation; muscle spasm; or dizziness, headache. Stomach Cramps 11. How long does hydrochlorothiazide stay in your system? Drug Intell Clin Pharm 18 (1984): 238-9, 42. Pollare T, Lithell H, Berne C "A comparison of the effects of hydrochlorothiazide and captopril on glucose and lipid metabolism in patients with hypertension." Polanska AI, Baron DN "Hyponatraemia associated with hydrochlorothiazide treatment ." Seelig CB "Magnesium deficiency in two hypertensive patient groups." Advertising revenue supports our not-for-profit mission. Read reviews from GoodRx users who have taken … Share your own story about diuretics in the comment section below. [Ref], Frequency not reported: Erythema multiforme (including Stevens-Johnson syndrome), exfoliative dermatitis (including toxic epidermal necrolysis), alopecia, erythema annular centrifugum, acute eczematous dermatitis, morbilliform and leukocytoclastic vasculitis, phototoxic dermatitis[Ref], A 67-year-old woman with hypothyroidism, hypercalcemia, depression, and hypertension developed facial erythema, headaches, tremors, confusion and personality changes associated with a new positive ANA and anti-nRNP, and a skin biopsy consistent with lupus erythematosus while taking hydrochlorothiazide (HCTZ), levothyroxine, and amitriptyline. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Other side effects not listed may also occur in some patients. No adverse side effects. The phase IV clinical study is created by eHealthMe based on 131,838 reports from the FDA, and is updated regularly. Drinking alcohol can increase side effects 1. This content does not have an Arabic version. Losartan/hydrochlorothiazide can cause mild or serious side effects. welts. Hydrochlorothiazide is a prescription medication that is used for controlling blood pressure and treating water retention (edema). Potentially dangerous unwanted effects can include headaches, but it is usually mild. No adverse side effects… Losartan/hydrochlorothiazide can cause mild or serious side effects. An allergic reaction is an example of a serious side effect and requires immediate medical attention. Although not all of these side effects may occur, if they do occur they may need medical attention. Writer Bio. Am J Med 109 (2000): 429-30, 81. Feel Like Throwing Up 5. Head Pain 6. My knees hurt really bad also. Check with your doctor immediately if any of the following side effects occur while taking hydrochlorothiazide: Some side effects of hydrochlorothiazide may occur that usually do not need medical attention. [Ref], Frequency not reported: Renal insufficiency (manifest as an increase in serum creatinine and BUN may occur due to hydrochlorothiazide-induced intravascular volume depletion), interstitial nephritis, renal failure[Ref], Although hydrochlorothiazide has been used to treat nephrogenic diabetes insipidus, a case report in which the drug was believed to have caused this condition has been reported. Fager G, Berglund G, Bondjers G, Elmfeldt D, Lager I, Olofsson SO, Smith U, Wiklund O "Effects of anti-hypertensive therapy on serum lipoproteins. South Med J 83 (1990): 739-42, 25. severe sunburn. Mouallem M, Friedman E, Shemesh Y, Mayan H, Pauzner R, Farfel Z "Cardiac conduction defects associated with hyponatremia." Practitioner 199 (1967): 209-10, 24. If you notice any other effects, check with your healthcare professional. Copyright © 2021 IBM Watson Health. This site complies with the HONcode standard for trustworthy health information: verify here. Goette DK, Beatrice E "Erythema annulare centrifugum caused by hydrochlorothiazide-induced interstitial nephritis." The mortality rate is 6%. Associated symptoms include dyspnea, hypoxia, respiratory distress, wheezing, cough, tachypnea, dizziness, nausea, vomiting, diarrhea, and hypotension. All rights reserved. Check with your doctor immediately if any of the following side effects occur: Some side effects may occur that usually do not need medical attention. High Blood Sugar 3. Frassetto LA, Nash E, Morris RC, Sebastian A "Comparative effects of potassium chloride and bicarbonate on thiazide-induced reduction in urinary calcium excretion." It is typically reversible within six months after discontinuation of therapy. Constipation 5. Hollifield JW, Slaton PE "Thiazide diuretics, hypokalemia and cardiac arrhythmias." Abnormally Low Blood Pressure 2. Available for Android and iOS devices. The following HealthHearty article tells you more about its side effects. Br Med J 1 (1978): 48, 35. Ann Surg 163 (1966): 291-6, 67. Throwing Up Mayo Clinic does not endorse companies or products. Side effects are reported by people who take Hydrochlorothiazide. , check interactions and set up your own personal medication records ( ). 161-2, 29 1960s although these patients were on a wide variety of health topics and Severe reactions... 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